Jørgen F P Wojtaszewski Selected Research

Glycogen Synthase (Synthase I)

1/2018	Effects of menopause and high-intensity training on insulin sensitivity and muscle metabolism.
1/2017	Acute Hypoglycemia in Healthy Humans Impairs Insulin-Stimulated Glucose Uptake and Glycogen Synthase in Skeletal Muscle: A Randomized Clinical Study.
1/2017	Exercise Increases Human Skeletal Muscle Insulin Sensitivity via Coordinated Increases in Microvascular Perfusion and Molecular Signaling.
1/2017	Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK.
7/2015	Dysregulation of muscle glycogen synthase in recovery from exercise in type 2 diabetes.
11/2012	Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4.
5/2012	GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance.
11/2009	Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus.
9/2008	Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.
8/2007	Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

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Jørgen F P Wojtaszewski Research Topics

Disease

49	Insulin Resistance 01/2021 - 03/2002
17	Type 2 Diabetes Mellitus (MODY) 01/2022 - 06/2003
6	Obesity 01/2020 - 10/2009
4	Birth Weight (Birth Weights) 01/2016 - 11/2007
3	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 11/2020 - 02/2008
3	Hyperinsulinism (Hyperinsulinemia) 10/2009 - 06/2003
2	Body Weight (Weight, Body) 01/2019 - 05/2014
2	Weight Loss (Weight Reduction) 09/2015 - 09/2015
2	Inflammation (Inflammations) 12/2012 - 01/2011
2	Lipodystrophy 08/2007 - 12/2005
2	Glycogen Storage Disease Type V (McArdle's Disease) 06/2002 - 06/2002
1	Morbid Obesity 01/2022
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021
1	Fatigue 01/2020
1	Hyperandrogenism 01/2019
1	Metabolic Diseases (Metabolic Disease) 05/2017
1	Hypoglycemia (Reactive Hypoglycemia) 01/2017
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2017
1	Glucose Intolerance 09/2011
1	Glycogen Storage Disease (Glycogenosis) 06/2002

Drug/Important Bio-Agent (IBA)

39	Insulin (Novolin)FDA Link 01/2022 - 04/2002
37	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 03/2002
15	Glycogen Synthase (Synthase I)IBA 01/2018 - 06/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2007
6	AMP-Activated Protein KinasesIBA 04/2018 - 01/2003
5	LipidsIBA 01/2019 - 01/2011
5	GlycogenIBA 03/2013 - 04/2002
4	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 05/2014
4	AICA ribonucleotide (ZMP)IBA 01/2019 - 06/2015
4	Messenger RNA (mRNA)IBA 01/2017 - 10/2009
3	AdiponectinIBA 01/2019 - 03/2013
2	Metformin (Glucophage)FDA LinkGeneric 12/2019 - 01/2013
2	HexokinaseIBA 01/2018 - 05/2012
2	CatecholaminesIBA 01/2017 - 01/2003
2	Triglycerides (Triacylglycerol)IBA 09/2015 - 09/2009
2	Oxygen (Dioxygen)IBA 07/2015 - 09/2009
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 10/2009 - 12/2005
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 09/2009 - 02/2006
2	Pioglitazone (Actos)FDA Link 09/2008 - 02/2008
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 08/2007 - 12/2005
1	Glucose Transporter Type 4IBA 01/2021
1	Muscle Proteins (Muscle Protein)IBA 01/2021
1	Colchicine FDA LinkGeneric 01/2020
1	FollistatinIBA 01/2020
1	activin AIBA 01/2020
1	C-PeptideIBA 01/2020
1	Adenosine Diphosphate (ADP)IBA 01/2020
1	Sirtuin 1IBA 01/2019
1	RibonucleotidesIBA 04/2018
1	O-GlcNAc transferaseIBA 01/2018
1	EnzymesIBA 01/2018
1	CarbohydratesIBA 10/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Epinephrine (Adrenaline)FDA LinkGeneric 01/2017
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2017
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2017
1	Prazosin (Minipress)FDA LinkGeneric 12/2014
1	Glucagon (Glukagon)FDA Link 05/2014
1	CeramidesIBA 03/2013
1	AdipokinesIBA 03/2013
1	3-Hydroxyacyl-CoA DehydrogenaseIBA 05/2012
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 05/2012
1	phospholipid emulsion soybean oil (Intralipid)IBA 01/2011
1	Protein Subunits (Protein Subunit)IBA 04/2010
1	Insulin ReceptorIBA 09/2009
1	ThiazolidinedionesIBA 02/2008
1	IsotopesIBA 08/2007
1	Glycogen Synthase KinasesIBA 08/2007
1	Glycogen Synthase Kinase 3 betaIBA 08/2007
1	Nonesterified Fatty Acids (NEFA)IBA 08/2007
1	acipimoxIBA 08/2007
1	Insulin Receptor Substrate ProteinsIBA 08/2007
1	Protein Isoforms (Isoforms)IBA 02/2004
1	Protein Kinases (Protein Kinase)IBA 06/2002
1	Caffeine (No Doz)FDA LinkGeneric 03/2002

Therapy/Procedure

4	Bed Rest (Bedrest) 01/2014 - 09/2011
3	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2019 - 05/2014
2	Endurance Training 04/2005 - 02/2004
2	Resistance Training 04/2005 - 02/2004
1	Bariatric Surgery 01/2019
1	Glycemic Control 05/2014
1	Highly Active Antiretroviral Therapy (HAART) 12/2005